KANSAS CITY, Mo. -- Colorado's path to the Big 12 championship game and a potential College Football Playoff bid got much more complicated Saturday after Kansas pulled off a dominant 37-21 win over the No. 16 Buffaloes.


Kansas running back Devin Neal produced 287 yards from scrimmage and four touchdowns to power an offense that proved unstoppable. The Jayhawks (5-6, 4-4) outrushed Colorado 331-42 and finished with zero punts or turnovers in a game they never trailed at GEHA Field at Arrowhead Stadium.


After winning four in a row, the Buffaloes (8-3) were in prime position to reach the Big 12 title game in Arlington, Texas, if they won out. Now, they're stuck in a three-way tie atop the conference standings with Arizona State and BYU at 6-2, with 5-2 Iowa State looking to make it a four-way tie with a win over Utah on Saturday night.


David Purdum: The point spread on the Indiana Hoosiers-Ohio State Buckeyes game moved three points Thursday, dropping from Buckeyes -13 to -10, with sportsbooks reporting a surge of bets on the underdog Hoosiers.


The line on the critical Big Ten clash had grown to as high as Ohio State -13.5 early in the week but began moving toward the underdog Hoosiers on Thursday, eventually settling at a consensus -10.


ESPN BET took more money on the Buckeyes from Thursday to Friday, but moved its point spread in line with the overall market. Other sportsbooks reported taking action on the Hoosiers from sharp customers on Thursday, causing the line to move.


DraftKings reported on Friday that Indiana plus the points was the most popular college football bet on the board by both number of bets and amount of money wagered. The Indiana-Ohio State game had also attracted more bets than any other game at BetMGM sportsbooks.


Joe Brennan, chief of Prime Sports, said his online sportsbook saw sharp bets come in Thursday on Indiana, but he wasn't convinced the line was done moving. "We think this line goes back up before post," Brennan told ESPN in a text message.


In fact, the line had ticked back up to Ohio State -10.5 at some sportsbooks Friday.


Ohio State announced Wednesday that starting center Seth McLaughlin would miss the game after suffering an Achilles tendon injury in practice. McLaughlin is the third Buckeyes offensive lineman to be lost to injury since October. Blustery weather also could play a factor in Saturday's game in Columbus, Ohio, where forecasts are calling for temperatures in the 40s with possible higher wind gusts.